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Friday, March 30, 2007

Holy Crap, I Just Canceled Myself!

We had our 8:45am appointment with Dr. Pompy today. An U/S appt to see how the follicles were doing. On the way to the appointment J protested that he didn't want to do another IVF cycle after this one. That he was tired of "throwing good money at bad". Yes, his words. I protested that I wasn't ready to throw in the towel just yet but he voiced that if I wanted to keep trying that it would be on my own. Fine. And shall I look for donor sperm, too, while I'm at it? "No, I didn't say that". Me, paraphrasing, "Okay. So you want the privilege of being a parent but you don't want to write your 50% of the check to help us be parents?" OMG. It was a terrible and hurtful argument. Infertility hurts couples in so many ways: emotionally, financially, and then there are the physical considerations. The shots, the hormones swings, possibility of overstimulating, etc. It's endless. But arguments like this are poison. Toxic.

So today is something like day 8 or 9 of stims. I tender in the ovary region and seriously bruised from the lovenox.

A bit of history: recall that we started off with 12 follicles...but they found a cyst...so they put me on stronger lupron in order to make the cyst go away. Dr. Russian said that antrals vary. They come and go. This was in response to his finding 7 on our last U/S about a week or so ago. I panicked but he seemed to imply that the others would likely be coming back.

But they didn't come back.

Today they only found 7 follicles. One at 7mm, a few at 11 and 12mm, and one at 14.4mm. I expressed concern over the 7mm follicle that it might not be able to "catch up" to the others. Dr. Pompy said "it might" catch up. So in reality we only had 6 follicles to work with.

I was devastated. This was my worst cycle ever. I always wind up with more follicles than they think I'll have. Heck, Dr. Moustache would always find extra follicles in the OR when he was poking around with the retrieval needle.

Withdrawing the wand, Dr. Pompy said that he wanted to test my estrogen to see if it was high enough to proceed. He didn't seem enthusiastic about it given how many follicles had disappeared.

I asked a multitude of questions as to how they might have disappeared:

"I worked out quite a bit the last two months. Might this have caused this?"

"No."

"I was on lupron since February 8t. Could it have put my follicles to sleep."

"No." (I have my doubts about this. Honestly, I think this was the culprit.)

"Okay. I've never done a cycle with menopur before. Do you think the LH did something to suppress my follicles to the point of disappearing?"

"No." (There are docs that would argue in my favor)

What he did say is that he felt that I'd done quite well for my age up til now and that it was possible that in the last year that it's caught up with me.

"But what about the 12 follicles? 12 is more like what I normally produce." I protested. There was really no answer for this.

Dr. Pompy said that they'd call with E2 results and would let me know what dosage to take for my evening shot. He said that if my E2 was lower than 250 that I'd be canceled and we'd try again next month. If this were the case I'd trigger with my hCG to induce ovulation so that I could get the "ball on the road" as soon as possible, rather than waiting up to six weeks for AF to arrive.

So we left and we argued all the way home as to what to do. It just doesn't sit right with me that 5 of my follicles disappeared. This has never happened to me before. With our first two IVF cycles I had 12 and 15 (or was it 16?) follicles. We had fantastic retrieval & fertilization rates.

About 4:30pm they called with my E2 results. 445. I asked what sort of number this represented in the spectrum of typical results. "Average". Okay. So I have less than normal follicles for me, and my E2 is average.

Evening came and I took my shots as planned save for the menopur and lovenox. It wouldn't matter if we proceeded or not: I'd still have to take them in order to trigger tomorrow. No reason to take the latter two shots as I'd made up my mind.

8:30pm came and I made the call. I telephoned our sweetie pie nurse and confided in her that J didn't want to do another IVF cycle after this one and that I didn't feel that we were truly giving it our best shot. I'd been thru the ringer with the cysts, the 2 months of lupron, and now I'd lost a huge percentage of my follicles. I explained that I didn't think that this was an optimal cycle for me and that I felt it was best that we cancel and start again with the next AF. I think I probably told her a bit too much about our reasons for canceling. Hopefully I didn't burden her with undue information.

I'm not sure why I felt the need to apologize to her, and to Dr. Pompy, but I did. I feel that I kind of let them down in a way, but as La Coloratura said, I paid them for each visit, ultrasound, and blood draw. I had a right to do whatever I wanted with this cycle. I fought back tears of disappointment during our conversation. But it's done. We're canceled. I'm kind of shocked we canceled ourselves, but hopefully next month will be better.

It's a hell of a let down after all we just went through.

[Millie if you're reading...I'd love to hear what you think of all of this.]

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Comments on "Holy Crap, I Just Canceled Myself!"

 

Blogger Nicole said ... (9:36 AM) : 

I am so sorry about the cancellation. My thoughts are with you.

 

Blogger Aunt Sassy said ... (9:55 AM) : 

So sorry to hear of your disappearing follicles (WTF???). Sounds like you made the right choice for you, and that's what is most important. will be checking in.

 

Blogger Rachel said ... (10:34 AM) : 

I am so sorry. This sounds terrible. I completely understand -- I had only 7 follicles and they got only two eggs. I felt like it was a wasted cycle. This is just a stressful process, and it seems like the doctors don't understand how difficult each cycle is. Good luck to you.

 

Blogger Jason and Samantha said ... (4:00 PM) : 

I'm so sorry. (hugs) Maybe you can give it a go, when you feel more "up to it", and the mister is more on board!

My prayers and thoughts are with you!!

 

Blogger Knock Me Up said ... (8:39 PM) : 

I would have felt the exact same way. I'm sorry you had to do it but it sounds like you made the best decision in a crappy situation. If you have had good response, you can again, so go forward and try again when the time is right.
Thanks for your post on my blog. I've read you for a while but have just been lurking. Happy to be out of the lurker closet.
Merideth

 

Blogger tonya said ... (8:54 PM) : 

What a tough place to be. It sounds like you did exactly what you needed to given all that has happened.

Hoping next cycle is much more successful than this round. Thinking of you.

 

Blogger Bumble said ... (10:56 PM) : 

Oh no Linda, I'm so sorry you're cancelled! Good Luck for the next round though, I hope it goes alot better. x

 

Anonymous Anonymous said ... (11:27 AM) : 

Linda,

I am so sorry to hear that you cancelled your cycle, but it sounds like you went with you gut intuition and that is very important. As you know by now, this IVF stuff is a lot of guessing and timing and luck. I completely understand your disappointment and continue to be impressed with your strength.

Hang in there, Sweetie. I'm thinking of you.

Love,

Amanda P.

 

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Ultrasound of a 9 week old fetus

Diagnosis:
elevated NKs, NKUs, 3 +APAs (2 borderline), heterozygous for MTHFR A1298C. Slightly low thyroid.

dq-α:
me: 1.1, 4.1
dh: 1.2, 3.1

Low LADs were treated in Mexico and elsewhere with LIT.
Anti-sperm antibodies
Article: LIT and the FDA

No: ANAs, normal TH1/TH2 Cytokine ratio, or x-DNA/Histones.

IF Treatments:
-Clomid #1: Sept 2005
-Clomid #2: Sept 2005
-HSG: Oct 2005
-Lap/Chromo: Oct 2005
-Nat'l IUI: Nov 2005
-IVF #1: Jan 2006, β1=2.0, β2=0.9
-IVF #2: May 2006, β1=<1.0
-Myomectomy (5), salpingectomy (both), & endo removed via lap on 6.6.6
-LIT#1 in Nogales: 6.16.6
-LIT#2: July 2006
-FET #1: Sept 2006, β1=2.48, β2=<2.0
-Dr. Hungarian Dx Oct 2006
-Dr. Hungarian Tx Dec 2006-Mar 2007
-IVF#3: Mar 2007 Canceled myself right before retrieval
-IVF#4: April/May 2007 Canceled due to dominant follicle
-IVF#4: August 2007, β1<2.0
-IVF#5: December 2007

Pre-ET
Feng Shui'd the House
500mg Zithromax starting with stims
4 LIT Treatments
17 Weeks of Humira or Enbrel
30g IVIg CD5 of IVF cycle (day 2 or 3 of stims)
30g IVIg 2 days before transfer
1mg Dexamethazone starting with stims
30mg Lovenox, 2X's/Day
0.0375mg Synthroid
Lexapro
Prenatal
Folguard 2.2 2x's/day
Extra 1g C (Stop at ET)
Extra 1g Calcium
Extra 400mg E (Stop at ET)
Nettle Tea & Capsules
2g Bromelain
Extra D3
Keep BMI<24
4-6g Fish Oil/Day
Baby Aspirin
Eating Loads of Protein!
Nettle Caplets
Femoral Massage (Stop at ET)
Acupuncture (Stop at ET)
TCM Diet: No cold or slippery foods
Immune Friendly Diet: No non-sprouted wheat, sugar, starches. Little fruit.
No nightshades
No caffeine
No coffee, not even decaf
No soy when in cycle
10 days Doxycycline

Day of Transfer
Light activity

Post ET Changes
Visualization
200mg progesterone capsules
Take it easy days 2&3
No sex til beta#1
Cut out egg yolks (contains immunogenic acid)






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