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Who are the lucky bloggers this month?

Working on it:
Mad Hatter
Ambivalent Womb
Stirrup-Queens
Delinquent Eggs
Wishing For One
I Can't Whistle
Hell Hath No Fury Like a Woman Barren
Everyone Else But Me
TTCNSLC
Endo-A-Go-Go
It Takes a Village
She's Back!: Manana Banana
Music Maker Momma

On other paths:
Fertile Soul
MLO Knitting
Pamplemousse
Out, damned egg! Out I say!
Holding Pattern
Hummingbird Chronicles
LAF
Try Whistling This
TTC Journey
Torrefaction
Velvet Cage

Success:
Adventures in Baby Making
Not According to Plan
Barren Albion
Barren Mare
Dead Bug
Due Dates
Fertility Shmertility
Flotsam
Fumbling Towards Eggstacy
Great Good Fortune
Healing Arts
Hopeful Mother
IF & the City
The Infertility Times
It Only Takes One Egg
(Non)Conception Confessions
Waiting for Baby Orange
Barefoot and...
It's So Not About You
...and Black Coffee Blues
Jenny From the Infertility Block
Smarshy Boy
Stella and/or Ben
Thin Pink Line
Tinkering with the Works
TKO, More or Less
Twisted Ovaries
UtRus
When Eggs Go Bad...

Other Good Reads:
Dr. Licciardi's Infertility Blog

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Mc Gill Reproductive Centre - Montreal
Georgia Reproductive Specialists
Jinemed Hospital - Turkey

Cooper Center - NJ
Conceptions - Colorado
Red Rock Fertility - Dr. Eva Littman
Pacific Fertility Center
Zouves Fertility Center"
Nova IVF
SIRM

IVF Meds - UK
Free Garage Sale
Flying Pharmacy (IVIg)

Blastocyst Grading Criteria
How much hCG is Left After Trigger?
POAS Ratings
More POAS Ratings
The Beta Base

Tuesday, February 23, 2010

And Then There Was One

Yesterday was transfer day. I arrived early to inquire about a $517 bill from the clinic for services that should have been paid, to do a progesterone test, and for my pre-transfer acupuncture session.

It was my first meeting with the acupuncturist. He was charming and really quite good placing the needles. I really appreciated being able to do my acupuncture session inside my RE's office - a huge stress reducer.

As I laid there with my needles in, I tried to visualize myself in a safe place, white light, and becoming pregnant. It was strange but something about the experience brought forth lots of really vivid visuals. I found myself wiping a unexpected few tears away.

He took the needles out at 4:45, which is when my transfer was due to happen. I guzzled down a bunch of water since I'd forgotten to drink anything but luckily my bladder was already moderately full. I was whisked into the transfer room and waited just a few minutes until Dr. Italian came in.

"We have one embryo today."

My heart sank. We had two blasts earlier in the day. What happened? He explained that the one that was "non expanding" was doing quite well (a grade 3 in terms of "blast" grading, not embryo grading - so very very good). The other one was not compacting well and hadn't formed the appropriate junctions between the cells. He said that they would watch it til the next evening. If it came around they'd freeze it for me. I suggested why not just put it in? But he said, "Well, that would defeat the purpose of doing a 5 day transfer."\

True. But it DID make it to blast. It's past that 3 day mark. So why not just put in back

I guess one thing is that it's safer in the lab under constant conditions if it's fragile. My uterus is a fairly hostile environment given how many embryos HAVEN'T made it there.

But he did say something that made my heart jump:

"This one may very well get you a baby."

So they washed my insides with water, blotted, and then rinsed out my cervix with blast culture so that there wouldn't be anything to "shock" the blast.

And in went the one little blast.

My post-transfer acupuncture would be done in the same room, so I just laid back and relaxed as best I could with a bladder that was near to popping. I really get freaked out peeing after transfer - worrying that I'll push out the embryos. The nurse could tell I didn't really want to get up and when I joked about getting a bedpan, she dashed off and brought me one. She is an angel. OMG. All I know is that with the bedpan and the acupuncture being done ON THE TRANSFER TABLE I was able to stay stationary for about an hour and a half before getting dressed to leave. That, in my book, makes me feel a LOT better about transfer than just about anything. (Well, that and the lovely valium that they gave me before I went in! ;-)

Progesterone levels are at 68 which they said was good. They said they want it to be over 17 or 18. They asked if I was taking extra on the side. Hell no. I wouldn't dare mess with my lining. There are somethings that I will tweak: antibiotic duration, lupron/ganirelix dosaging...but progesterone before transfer is definitely NOT among them. I would add in extra progesterone well after transfer (maybe 4 or 5 days out to support a potential pregnancy, but not before).

Anyways. That's it. 1 very good blast, one is struggling in the lab today.

Taking it easy today...riding the couch with the cats.

Beta is on March 2nd, but I'll be POAS with abandon the entire time.

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Monday, February 22, 2010

Day 5 Embryo Report

I was a bit nervous this morning as I only had Saturday's day 3 report to go on. I sent in an email to the office. A prompt reply came back:

"You have one non-expanded and one compacted, both grade 3. There will be one last update right before transfer"

OK. I've not been to a day 5 transfer before. I'm in the dark on these things. I found this great description of how blasts are graded here which helped a lot but I still asked for a bit of clarification. She wrote back right away. Thank god. As I am a bit nervous.

"The best case is an expanded blastocyst, the non expanded and compacted. The non and compacted are just embryos that haven’t totally expanded. You will be able to get a better explanation at transfer from Dr Italian or our embryologist."

So I am wondering about the grading now. I had 2 7-celled grade 2 embryos on day 3. But now they are blasts. Blasts tend to have their own rating scale (esp if you look at the link above). Are my blasts still being graded on an embryo scale (and have thereby slipped from grade 2 to grade 3) or are they onto the Gardner blast grading scale which makes them a 3 and is actually quite good?

Well, I guess I'll have to wait til I get to the lab to know for sure.

All I know is that I am grateful, elated beyond belief, that this 45 year old has produced two living blasts for my 5 day transfer. I know that I have beat the odds: only 50% of embryos apparently make it to day 5.

This can happen. I believe this can happen.

Touch wood. Throw salt. Spit. Make sign against evil eye. Anything I'm missing in my ritual?

I'm doing pre and post acupuncture at the clinic (thank god it's all done in house) which should bump my odds a bit higher.

Now if I can just remember to breathe!!!!

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elevated NKs
NKUs
3 +APAs (2 borderline)
heterozygous MTHFR A1298C
Slightly low thyroid.

dq-α:
me: 1.1, 4.1
dh: 1.2, 3.1 we parted

Low LADs were treated in Mexico and elsewhere with LIT
Anti-sperm antibodies
Article: LIT and the FDA

No: ANAs, normal TH1/TH2 Cytokine ratio, or x-DNA/Histones.

SMA Carrier

IF Treatments:
-Clomid #1: Sep 2005
-Clomid #2: Sep 2005
-HSG (tubes barely open): Oct 2005
-Lap/Chromo (cyst removed; tubes clogged): Oct 2005
-Nat'l IUI: Nov 2005
-IVF #1: Jan 2006, β1=2.0, β2=0.9
-IVF #2: May 2006, β1=<1.0
-Myomectomy (5), salpingectomy (both), & endo removed via lap on 6.6.6
-LIT#1 in Nogales: Jun 2006
-LIT#2: Jul 2006
-FET #1: Sep 2006, β1=2.48, β2=<2.0
-Dr. Hungarian Dx Oct 2006
-Dr. Hungarian Tx Dec 2006-Mar 2007
-IVF#3: Mar 2007 Canceled myself right before retrieval
-IVF#3 Take 2: Apr/May 2007 Canceled due to dominant follicle
-IVF#3 Take 3: Aug 2007, β1<2.0
-IVF#4: Mar 2009 - Canceled due to my flipping out over donor sperm
- Hysteroscopy - Jul 2009 -IVF#4 Take 2: Jul 2009 - Canceled due to fibroid found during hysteroscopy - Myomectomy: Jul 2009
-IVF#4 Take 3: Aug 2009 - Canceled due to ovarian cyst
-IVF #4 Take 4: Oct 2009 - Antagon Cycle β1<1.0
- HSG, Cyst Aspiration on Left Ovary, Sclerotherapy on Endometrioma on Right Ovary: 29 Oct 09
-IVF #5: Nov-Dec 2009 - Adding in HGH one way or another

Pre-ET
Feng Shui'd the House
500mg Zithromax starting with stims
4 LIT Treatments
17 Weeks of Humira or Enbrel
30g IVIg CD5 of IVF cycle (day 2 or 3 of stims)
30g IVIg 2 days before transfer
1mg Dexamethazone starting with stims
40mg Lovenox, 1X's/Day, 2X's a day if BFP
0.0375mg Synthroid
Lexapro
Prenatal
Folguard 2.2Methyl folate
Extra 1g C (Stop at ET)
Extra 1g Calcium
Extra 400mg E (Stop at ET)
Nettle Tea & Capsules
2g Bromelain
Extra D3
Keep BMI<24
4-6g Fish Oil/Day
Baby Aspirin
Eating Loads of Protein!
Nettle Caplets
Femoral Massage (Stop at ET)
Acupuncture (Stop at ET)
TCM Diet: No cold or slippery foods
Immune Friendly Diet: No non-sprouted wheat, sugar, starches. Little fruit.
No nightshades
No caffeine
No coffee, not even decaf
No soy when in cycle
10 days Doxycycline

Day of Transfer
Light activity

Post ET Changes
Visualization
200mg progesterone capsules
Take it easy days 2&3
No sex til beta#1
Cut out egg yolks (contains immunogenic acid)

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