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Working on it:
Confessions of an Infertile
Desperate to Multiply
Infertility Sucks...
Our IVF Journey
Out, damned egg! Out I say!
Pamplemousse
Square Peg, Round Whole

Other paths:
Fertile Soul
Holding Pattern
Hummingbird Chronicles
LAF
My Eggs Are Cooked
Try Whistling This
TTC Journey
Torrefaction
Velvet Cage

Success:
Adventures in Baby Making
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Barren Mare
Bindweed Heights
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Due Dates
Fertility Shmertility
Fisher Queen
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IF & the City
The Infertility Times
It Only Takes One Egg
Manana Banana
Me the Bumblebee
(Non)Conception Confessions
Ornery Lotus Blossom
Waiting for Baby Orange
Barefoot and...
It's So Not About You
...and Black Coffee Blues
Jenny From the Infertility Block
Prop Your Hips
Smarshy Boy
Stella and/or Ben
Thin Pink Line
Tinkering with the Works
TKO, More or Less
Twisted Ovaries
UtRus
When Eggs Go Bad...

Other Good Reads:
Dr. Licciardi's Infertility Blog
Mainely Madge
Pale Frog
Pharyngula
This Und That

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Mc Gill Reproductive Centre - Montreal
Georgia Reproductive Specialists
Jinemed Hospital - Turkey

Cooper Center - NJ

IVF Meds - UK
Free Garage Sale
Flying Pharmacy (IVIg)

Wednesday, April 25, 2007

Phone Consult with Dr. Generous

On Monday I had my phone consult with Dr. Generous from the clinic in the big city north of me. I had basically forgotten that she was going to be calling and was deep in my research at the county records when the call came in. I was immediately anxious that I hadn't charged my cell phone and hoped that it wouldn't cut out on us partway through our conversation.

As you may know, Dr. Generous used to work with Dr. Moustache, and so their protocols are quite similar in that they also do the MD Flare protocol, which worked fine for me the first two cycles. I explained our sordid IF history to her and recounted every offbeat therapy we've tried thus far: heparin, IVIg, lovenox, humira, the laparotomy to remove 5 fibroids/endometriomas/2 fallopian tubes/scar tissue/adhesions, two trips to Mexico for LIT and, of course, the therapy with Dr. Hungarian. She reminded me, "We do not do immune therapy here" to which my reply was "Yes, I realize that" but inside I was thinking, "But of course I'll do what I have to on my own." I think I'd still do lovenox and IVIg as they're not contraindicated in any way, shape, or form in an IVF cycle. That's not exactly true, now that I think of it. I have read many cases of heparin and lovenox causing subchorionic hemmorhages (SCH) in placentas, but that happens once pregnancy is established. So I can always ease off of the lovenox once (knock on wood) pregnancy occurs.

On the topic of my laparotomy last June, she expressed concern that if my ob/gyn (Dr. G) had used excessive cauterization in the removal of my endometriomas that it could cause permanent damage and make it so that follicles weren't able to form. Scary thought. I'll have to call Dr. G to see what she did while she was in there.

I asked her the typical "So what would you do differently question. After a bit of conversation, it was clear that she'd return me to the MD Flare protocol but would add in some femara to help with my endometriosis issues. She explained that femara can help to restore beta-3-integrins in women that are lacking them. Okay. This is good. Something new. Exactly up my alley so to speak.

I told her that I presently have a 30mm cyst on my left ovary and that my right ovary is enlarged with at least one 10mm cyst. (All measured on CD3 when things "should" be nice and quiet). She said that on CD1 I should call her office for an appointment the next day and that they'd do an U/S, and if those pesky cysts were still there that they'd just aspirate them. I do worry that Dr. Pompy said that aspirating cysts doesn't get rid of the problem of the cells that are IN the cyst in that they produce hormone. So I'm not sure that I'm yet on board here. More research is required. (And if any of you readers are up on this sort of thing, I would so appreciate hearing from you!)

One thing that I didn't expect from Dr. Generous was that she nearly immediately brought up the issue of egg donation. I told her that I was open to it, but realizing that if we went that route, it could be done at ANY time in the next 20 years. Dr. Moustache has proven that quite well. For now, I want to focus on trying with my own eggs till they've petered out completely and all hope is essentially gone. After reading the article about the doctors at Harvard that have debunked the the "theory" that us womenfolk are born with a complete set of eggs at birth, I have hope that I'll have a bit longer to try. Actually, I'm just praying that these docs will find a way to get those ovum stem cells out so that I can have a continual supply of eggs from which to try with. Of course they'd have to PGD the hell out of them to make sure that they were usable, but if I never had to go through another bout of Gonal F/menopur and retrieval it would suit me just fine.

So I'm in the typical holding pattern for the time being. I can tell I'm near ovulation, much good that does me, as I've got the typical FCM going on but it's tinged with blood so I'm concerned about infection once again. I'll probably start popping flagyl any day now and I'll add in the zithromax once we're in cycle.

So is this IVF#3 or IVF#4? We canceled ourselves just a couple days before retrieval. I guess I'll call it 4 even though we didn't make it to retrieval just for the sake of keeping cycles clear in my head, and in my blog.

I so can't believe that it's this fucking hard to get pregnant.

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Note: In the comments section a reader graciously left me a link to an article on whether aspirating functional cysts during an IVF cycle has any effect on the outcome of the cycle. Great reading. (Thank you!)

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Monday, April 02, 2007

What is the sound of 7 follicles exploding?

As I write this, it has been roughly 40 hours after my hCG trigger shot on Saturday evening and I feel like my ovaries have been kicked. Hard.

It's one thing for the good doctor to go in and clean out the follicles with a needle, under anesthesia, but to actually ovulate all 7 of them? Egad.

In a normal month my mittleschmertz pain is enough to feel like someone is sticking an icepick in my side. Make that times 7 this month.

Dr. Pompy's office is supposed to call today to talk to us about our next cycle. AF is two weeks away and at the CD3 point we'll do another baseline U/S to count antrals (and also look to ensure that there aren't any cysts AGAIN). I hope that I am right, and Dr. Pompy is wrong, in that my numbers fell from 12 to 7 this cycle due to overmedication with lupron. I mean, I DID have 12 follicles at some point. This losing-of-follicles business is unprecedented. Never happened before in my body as far as records show.

So why now? Why should my body just start doing random shit?

If my body wants to slip into perimenopause, why doesn't it just start off with 7 follicles. Why start off with 12 and then let 5 wither? It doesn't make biological sense to me. Maybe there's an explanation but I just don't know what it is.

I'm baffled.

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Ultrasound of a 9 week old fetus

Diagnosis:
elevated NKs, NKUs, 3 +APAs (2 borderline), heterozygous for MTHFR A1298C. Slightly low thyroid.

dq-α:
me: 1.1, 4.1
dh: 1.2, 3.1

Low LADs were treated in Mexico and elsewhere with LIT.
Anti-sperm antibodies
Article: LIT and the FDA

No: ANAs, normal TH1/TH2 Cytokine ratio, or x-DNA/Histones.

IF Treatments:
-Clomid #1: Sept 2005
-Clomid #2: Sept 2005
-HSG: Oct 2005
-Lap/Chromo: Oct 2005
-Nat'l IUI: Nov 2005
-IVF #1: Jan 2006, β1=2.0, β2=0.9
-IVF #2: May 2006, β1=<1.0
-Myomectomy (5), salpingectomy (both), & endo removed via lap on 6.6.6
-LIT#1 in Nogales: 6.16.6
-LIT#2: July 2006
-FET #1: Sept 2006, β1=2.48, β2=<2.0
-Dr. Hungarian Dx Oct 2006
-Dr. Hungarian Tx Dec 2006-Mar 2007
-IVF#3: Mar 2007 Canceled myself right before retrieval
-IVF#4: April/May 2007 Canceled due to dominant follicle
-IVF#4: August 2007, β1<2.0
-IVF#5: December 2007

Pre-ET
Feng Shui'd the House
500mg Zithromax starting with stims
4 LIT Treatments
17 Weeks of Humira or Enbrel
30g IVIg CD5 of IVF cycle (day 2 or 3 of stims)
30g IVIg 2 days before transfer
1mg Dexamethazone starting with stims
30mg Lovenox, 2X's/Day
0.0375mg Synthroid
Lexapro
Prenatal
Folguard 2.2 2x's/day
Extra 1g C (Stop at ET)
Extra 1g Calcium
Extra 400mg E (Stop at ET)
Nettle Tea & Capsules
2g Bromelain
Extra D3
Keep BMI<24
4-6g Fish Oil/Day
Baby Aspirin
Eating Loads of Protein!
Nettle Caplets
Femoral Massage (Stop at ET)
Acupuncture (Stop at ET)
TCM Diet: No cold or slippery foods
Immune Friendly Diet: No non-sprouted wheat, sugar, starches. Little fruit.
No nightshades
No caffeine
No coffee, not even decaf
No soy when in cycle
10 days Doxycycline

Day of Transfer
Light activity

Post ET Changes
Visualization
200mg progesterone capsules
Take it easy days 2&3
No sex til beta#1
Cut out egg yolks (contains immunogenic acid)






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